Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373741 | 0.87 | CA12 (0.53) | CA12CA9CDC25AAPEX1MEN1 | |
| SCHEMBL27807049 | 0.85 | ALDH1A1 (0.47) | CDC25AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10826562 | 0.82 | CA12 (0.45) | CA12CA9CDC25AAPEX1PDPK1 | |
| SCHEMBL29385257 | 0.79 | MEN1 (0.61) | MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL18974998 | 0.79 | ALDH1A1 (0.47) | CDC25AMEN1KMT2AALDH1A1KDM4E | |
| Dimethyl Sulfoxide SCHEMBL28864053 | 0.79 | ALDH1A1 (0.42) | CDC25AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7252498 | 0.78 | CA12 (0.39) | CA12CA9CDC25AAPEX1PDPK1 | |
| SCHEMBL29385380 | 0.77 | ALDH1A1 (0.63) | CDC25AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1596004 | 0.76 | ALDH1A1 (0.45) | CDC25AALDH1A1KDM4E | |
| SCHEMBL16048149 | 0.76 | ALDH1A1 (0.62) | CDC25AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768822-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-12-06 | — | — | EP | disclosed |