Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19673997 | 0.87 | CA12 (0.49) | CA12CA9APEX1MEN1KMT2A | |
| SCHEMBL9618341 | 0.83 | CA12 (0.65) | CA12CA9APEX1MEN1KMT2A | |
| SCHEMBL16432726 | 0.77 | CA12 (0.53) | CA12CA9MEN1KMT2AHDAC3 | |
| SCHEMBL15486077 | 0.77 | KDM4E (0.55) | CA12CA9MEN1KMT2AKDM4E | |
| SCHEMBL10826562 | 0.76 | CA12 (0.45) | CA12CA9APEX1MEN1KMT2A | |
| SCHEMBL2993397 | 0.75 | CA12 (0.41) | CA12CA9MEN1KMT2ACDC25A | |
| SCHEMBL5087842 | 0.73 | MEN1 (0.55) | CA12CA9MEN1KMT2A | |
| SCHEMBL12311066 | 0.73 | MEN1 (0.69) | CA12CA9MEN1KMT2A | |
| SCHEMBL27673616 | 0.72 | KDM4E (0.42) | CA12CA9APEX1MEN1KMT2A | |
| SCHEMBL13444611 | 0.72 | CA12 (0.47) | CA12CA9APEX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846939-B2 | Salts and mixture of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols, pharmaceutical compositions containing said agents and treatment methods | EPHAG AS (EE) | 2010-12-07 | — | — | US | disclosed |
| EP-1970372-B1 | SALTS OF 9-OXOACRIDINE-10-ACETIC ACID WITH 1-ALKYLAMNO-1-DESOXY-POLYOLS | EPHAG AS (EE) | 2010-11-03 | — | — | EP | disclosed |
| US-20100144780-A1 | Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods | PJSC PHARMSYNTHEZ (RU) | 2010-06-10 | — | — | US | disclosed |
| WO-2008121029-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID AND/OR SALTS AND/OR ITS ESTERS THEREOF FOR THE TREATMENT AND PROPHYLAXIS OF MALIGNANT TUMORS OF FEMALE REPRODUCTIVE SYSTEM | SURKOV KIRILL GENNEDIEVICH (RU) | 2008-10-09 | — | — | WO | disclosed |
| EP-1970372-A2 | SALTS OF 9-OXOACRIDINE-10-ACETIC ACID WITH 1-ALKYLAMNO-1-DESOXY-POLYOLS | EPhaG AS (EE) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144780-A1 | Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods | ADSL, ACMSD, ASS1 | CA12 823/4885CA9 42/4885APEX1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.