Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200019 | 0.85 | MTNR1A (0.60) | ATMHTR2CALDH1A1MAPTHSD17B10 | |
| SCHEMBL5449877 | 0.85 | ATM (0.57) | ATMALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL21810428 | 0.84 | NTSR1 (0.57) | ATMHTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL14876504 | 0.84 | NTSR1 (0.57) | ATMHTR2CALDH1A1HSD17B10MTNR1A | |
| SCHEMBL5637363 | 0.84 | ATM (0.56) | ATMHTR2CALDH1A1MAPTHSD17B10 | |
| SCHEMBL14487798 | 0.83 | ATM (0.52) | ATMALDH1A1MAPTHSD17B10MTNR1A | |
| SCHEMBL16234644 | 0.83 | HTR2A (0.54) | ATMHTR2AHTR2CHDAC8HDAC6 | |
| SCHEMBL5537950 | 0.83 | KMT2A (0.60) | HTR2AHTR2CALDH1A1MAPTHDAC8 | |
| SCHEMBL14594510 | 0.82 | ATM (0.55) | ATMALDH1A1MAPTHSD17B10MTNR1A | |
| SCHEMBL6029964 | 0.82 | ATM (0.58) | ATMALDH1A1HSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768822-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-12-06 | — | — | EP | disclosed |