Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Chloride SCHEMBL11668378 | 0.91 | DRD2 (0.39) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL15595233 | 0.86 | DRD2 (0.44) | PNMTDRD2DRD1DRD4DRD5 | |
| Ethyl Chloride SCHEMBL11668295 | 0.78 | DRD2 (0.42) | PNMTDRD2DRD1DRD4DRD5 | |
| Ammonia Solution, Strong SCHEMBL15466738 | 0.75 | DRD2 (0.50) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL15595295 | 0.73 | DRD2 (0.49) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL29767754 | 0.73 | DRD2 (0.49) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL450863 | 0.73 | DRD2 (0.49) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL25294084 | 0.73 | DRD2 (0.45) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL30439522 | 0.73 | DRD2 (0.45) | PNMTDRD2DRD1DRD4DRD5 | |
| SCHEMBL26837117 | 0.72 | DRD2 (0.47) | PNMTDRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252057-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2017-12-06 | — | — | EP | disclosed |