Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392985 | 1.00 | ADRB2 (0.35) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL19674488 | 0.91 | ADRB2 (0.36) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL18601882 | 0.91 | ADRB2 (0.36) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL15630094 | 0.91 | ADRB2 (0.36) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL18601868 | 0.87 | ADRB2 (0.34) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL16999077 | 0.86 | ADORA3 (0.38) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL14681026 | 0.80 | ADORA3 (0.40) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL27415356 | 0.79 | ADORA3 (0.37) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL384325 | 0.77 | ADRB2 (0.39) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL776314 | 0.77 | ADRB2 (0.39) | ADRB2DRD2DRD1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138837-B1 | INDACATEROL FREE BASE IN SOLID FORM | CRYSTAL PHARMA SAU (ES) | 2021-11-24 | — | — | EP | disclosed |
| EP-3848354-A1 | PROCESS FOR THE PREPARATION OF INDACATEROL AND INTERMEDIATES THEREOF | Crystal Pharma, S.A.U. (ES) | 2021-07-14 | — | — | EP | disclosed |
| EP-2897937-B1 | PROCESS FOR THE PREPARATION OF INDACATEROL AND INTERMEDIATES THEREOF | CRYSTAL PHARMA SAU (ES) | 2017-12-06 | — | — | EP | disclosed |