SCHEMBL196746

SCHEMBL196746

CC[Si](CC)(CC)Oc1ccc(Cl)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.37
CYP3A4 P08684 2/20 0.37
PPARA Q07869 2/20 0.37
ABCB11 O95342 1/20 0.37
TSHR P16473 1/20 0.37
HTR2A P28223 1/20 0.37
PMP22 Q01453 1/20 0.37
MAOB P27338 2/20 0.37
MAOA P21397 1/20 0.37
LMNA P02545 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2C9 P11712 2/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
KMT2A Q03164 3/20 0.36
CYP2D6 P10635 2/20 0.36
HPGD P15428 1/20 0.35
KCNH2 Q12809 1/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3868257 0.79 ACHE (0.44) CYP3A4TSHRLMNANPC1RAB9A
SCHEMBL5544475 0.77 NQO1 (0.33) CYP3A4CYP2D6
SCHEMBL13243761 0.77 NR1H2 (0.39) CYP3A4CYP2D6
SCHEMBL6859076 0.77 MAPT (0.37) MAOBLMNACYP2A6NPC1RAB9A
SCHEMBL19617247 0.77 MAPT (0.39) CYP1A2TSHRCYP2C19KCNH2MAPT
SCHEMBL713108 0.76 CA4 (0.42) TSHRLMNAKCNH2LTA4H
SCHEMBL13131167 0.76 NQO1 (0.32)
SCHEMBL13131103 0.76 NQO1 (0.32)
SCHEMBL19678075 0.74 MEN1 (0.41) CYP1A2CYP3A4TSHRNPC1RAB9A
SCHEMBL5400910 0.74 CYP1A2 (0.39) CYP1A2CYP3A4PPARAABCB11TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702372-B Method for preparing 4- (2-methoxyl) ethylphenol 台州市前进化工有限公司 2022-12-16 CN disclosed
CN-114702372-A Method for preparing high-purity 4- (2-methoxy) ethylphenol 台州市前进化工有限公司 2022-07-05 CN disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-8088883-B2 Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-03 US disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 CYP1A2 191/4885CYP3A4 61/4885PPARA 3957/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 CYP1A2 228/4885CYP3A4 135/4885PPARA 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.