Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196069 | 0.90 | RAB9A (0.59) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL196452 | 0.88 | GRM4 (0.47) | RAB9ANPC1MAPTALDH1A1TP53 | |
| SCHEMBL196377 | 0.86 | GRM4 (0.49) | RAB9ANPC1MAPTTP53RXFP1 | |
| SCHEMBL196780 | 0.85 | GRM4 (0.51) | RAB9ANPC1MAPTTP53RXFP1 | |
| SCHEMBL29501836 | 0.85 | GRM4 (0.51) | RAB9ANPC1MAPTTP53RXFP1 | |
| SCHEMBL30637139 | 0.85 | GRM4 (0.51) | RAB9ANPC1MAPTTP53RXFP1 | |
| SCHEMBL197210 | 0.83 | MAPK8 (0.58) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL196310 | 0.82 | RXFP1 (0.47) | RAB9ANPC1MAPTTP53KMT2A | |
| SCHEMBL196512 | 0.81 | MAPT (0.55) | RAB9ANPC1MAPTALDH1A1MAPK8 | |
| SCHEMBL197113 | 0.80 | MAPT (0.57) | RAB9AMAPTKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500255-A | — | — | 2012-01-05 | — | — | JP | claimed |
| EP-2323661-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | Universiteit Leiden (NL) | 2011-05-25 | — | — | EP | claimed |
| EP-2323661-A1 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS | Universiteit Leiden (NL) | 2011-05-25 | — | — | EP | disclosed |