Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428460 | 0.85 | PTGS1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL5035064 | 0.85 | HDAC6 (0.32) | HDAC6ALDH1A1RECQLKDM4EMAPT | |
| SCHEMBL3425627 | 0.85 | PAOX (0.34) | HDAC6ALDH1A1RECQLKDM4EMAPT | |
| SCHEMBL10166232 | 0.83 | — | — | |
| SCHEMBL3425614 | 0.81 | MEN1 (0.32) | HDAC6ALDH1A1 | |
| SCHEMBL20081691 | 0.81 | KDM4E (0.35) | HDAC6RECQLKDM4EMAPT | |
| SCHEMBL19229985 | 0.81 | PLA2G7 (0.31) | — | |
| SCHEMBL31188474 | 0.79 | KDM4E (0.42) | RECQLKDM4EMAPT | |
| SCHEMBL19675107 | 0.79 | KDM4E (0.35) | HDAC6ALDH1A1RECQLKDM4EMAPT | |
| SCHEMBL15672233 | 0.78 | SMN1; SMN2 (0.39) | HDAC6ALDH1A1RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985633-B1 | NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES | T2 BIOSYSTEMS INC (US) | 2017-12-06 | — | — | EP | disclosed |