SCHEMBL3425614

SCHEMBL3425614

CC(C)C(=O)CCCN1C(=N)N(C)CC1=O

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ THPO P40225 1/20 0.32
▸ PMP22 Q01453 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10166225 0.84 — —
SCHEMBL3428460 0.83 PTGS1 (0.41) MEN1LMNACYP2C9PTGS1KMT2A
SCHEMBL5035064 0.83 HDAC6 (0.32) ALDH1A1HDAC6
SCHEMBL3425627 0.83 PAOX (0.34) ALDH1A1HDAC6
SCHEMBL19675040 0.81 HDAC6 (0.31) ALDH1A1HDAC6
SCHEMBL20081691 0.79 KDM4E (0.35) HDAC6
SCHEMBL19229985 0.78 PLA2G7 (0.31) —
SCHEMBL10166228 0.77 HPGD (0.36) MEN1LMNAKMT2AALDH1A1GAA
SCHEMBL19038331 0.77 SMN1; SMN2 (0.43) MEN1KMT2AALDH1A1GAA
SCHEMBL31188474 0.77 KDM4E (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210181281-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2021-06-17 — — US disclosed
US-20190085381-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2019-03-21 — — US disclosed
US-20170233798-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2017-08-17 — — US disclosed
US-9714940-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2017-07-25 — — US disclosed
US-9702852-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2017-07-11 — — US disclosed
US-9702852-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2017-07-11 — — US disclosed
US-9488648-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2016-11-08 — — US disclosed
US-9046493-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2015-06-02 — — US disclosed
US-8883423-B2 NMR systems and methods for the rapid detection of analytes T2 BIOSYSTEMS, INC. (US) 2014-11-11 — — US disclosed
US-20140120523-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2014-05-01 — — US disclosed
US-20130273522-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2013-10-17 — — US disclosed
US-20130273523-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. 2013-10-17 — — US disclosed
US-20130266944-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 Biosystems. Inc. (US) 2013-10-10 — — US disclosed
US-20130260367-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-10-03 — — US disclosed
US-20130244238-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-09-19 — — US disclosed
US-20130095494-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-04-18 — — US disclosed
US-20130029345-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2013-01-31 — — US disclosed
US-20120301888-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2012-11-29 — — US disclosed
US-20120100546-A1 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2012-04-26 — — US disclosed
WO-2012054639-A2 NMR SYSTEMS AND METHODS FOR THE RAPID DETECTION OF ANALYTES T2 BIOSYSTEMS, INC. (US) 2012-04-26 — — WO disclosed
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