Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19676619 | 0.83 | ALDH1A1 (0.37) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL19675275 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL18727026 | 0.72 | TAS2R38 (0.48) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL26518694 | 0.70 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL19675222 | 0.70 | GAA (0.34) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL18453738 | 0.69 | ALDH1A1 (0.45) | MAPTALDH1A1KMT2AHSD17B10TAS2R38 | |
| SCHEMBL4669792 | 0.69 | ALDH1A1 (0.53) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL14347597 | 0.69 | TAS2R38 (0.64) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL13381399 | 0.69 | TAS2R38 (0.64) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL14347590 | 0.69 | TAS2R38 (0.64) | MAPTALDH1A1KMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252050-A1 | PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-3252049-A1 | PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-12-06 | — | — | EP | disclosed |