Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11930613 | 0.78 | POLB (0.39) | ALDH1A1POLBRAB9AIDO1AAK1 | |
| SCHEMBL30315297 | 0.70 | — | — | |
| SCHEMBL2927541 | 0.67 | — | — | |
| SCHEMBL3294173 | 0.67 | KDM4E (0.37) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| Cytosine SCHEMBL29787229 | 0.65 | POLB (0.42) | KDM4EPOLBRAB9ANOS3NOS2 | |
| Uracil SCHEMBL29525634 | 0.65 | — | — | |
| SCHEMBL4795553 | 0.65 | — | — | |
| SCHEMBL21792155 | 0.65 | — | — | |
| Cytosine SCHEMBL308339 | 0.65 | — | — | |
| SCHEMBL10325788 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| CN-108137509-B | Pyrrole, oxadiazole, triazole or tetrazole derivatives suitable for controlling arthropods | 拜耳作物科学股份公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-106083710-B | Process for the synthesis of halogenated cyclic compounds | 索尔维公司 | 2021-03-12 | — | — | CN | disclosed |
| EP-2334645-B1 | PROCESS FOR THE SYNTHESIS OF FLUORINATED CYCLIC COMPOUNDS | SOLVAY (BE) | 2019-11-06 | — | — | EP | disclosed |
| CN-106083710-A | For synthesizing the method for the cyclic compound of halogenation | 索尔维公司 | 2016-11-09 | — | — | CN | disclosed |
| US-8981115-B2 | Process for the synthesis of halogenated cyclic compounds | SOLVAY SA (BE) | 2015-03-17 | — | — | US | disclosed |
| US-20130237710-A1 | Process for the synthesis of halogenated cyclic compounds | SOLVAY SA (BE) | 2013-09-12 | — | — | US | disclosed |
| US-8431710-B2 | Process for the synthesis of halogenated cyclic compounds | SOLVAY SA (BE) | 2013-04-30 | — | — | US | disclosed |
| US-20110178297-A1 | Process for the synthesis of halogenated cyclic compounds | SOLVAY SA (BE) | 2011-07-21 | — | — | US | disclosed |
| EP-2334645-A1 | PROCESS FOR THE SYNTHESIS OF HALOGENATED CYCLIC COMPOUNDS | Solvay SA (BE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010037688-A1 | PROCESS FOR THE SYNTHESIS OF HALOGENATED CYCLIC COMPOUNDS | SOLVAY SA (BE) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178297-A1 | Process for the synthesis of halogenated cyclic compounds | CCNL2, AOC2, CCNY | KDM4E 2469/4885ALDH1A1 1301/4885CYP1A2 8/4885 |
| US-20130237710-A1 | Process for the synthesis of halogenated cyclic compounds | CCNL2, AOC2, CCNY | KDM4E 2469/4885ALDH1A1 1301/4885CYP1A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.