SCHEMBL3294173

SCHEMBL3294173

FC(F)(F)c1ccc(C(F)(F)F)[nH]1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.37
HSD17B2 P37059 5/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
NOTUM Q6P988 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22315193 0.80 HMBS (0.50) KDM4EHSD17B2HPGDNOTUM
SCHEMBL21940258 0.74 HIF1A (0.35) KDM4EHSD17B2ALDH1A1HPGDCYP1A2
SCHEMBL21871898 0.74 HSD17B2 (0.33) KDM4EHSD17B2
SCHEMBL18404761 0.72 HSD17B2 (0.48) KDM4EHSD17B2
SCHEMBL21122271 0.60 KDM4E (0.43) KDM4EALDH1A1HPGDNOTUMCYP1A2
Hydrochloric Acid SCHEMBL29010139 0.58 HSD11B1 (0.54) ALDH1A1HPGDNOTUMCYP1A2POLB
SCHEMBL63468 0.56 ALDH1A1 (0.67) ALDH1A1TSHR
SCHEMBL29441997 0.52 ALDH1A1 (0.52) ALDH1A1NOTUMCYP1A2CYP2C9MEN1
Iodide SCHEMBL29093539 0.52 ALDH1A1 (0.59) ALDH1A1TSHR
Hydrochloric Acid SCHEMBL10488807 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11005126-B2 Electrolytic solution for secondary battery, secondary battery, battery pack, electric vehicle, electric power storage system, electric power tool, and electronic device MURATA MANUFACTURING CO., LTD. (JP) 2021-05-11 US disclosed
US-20190207257-A1 ELECTROLYTIC SOLUTION FOR SECONDARY BATTERY, SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, ELECTRIC POWER STORAGE SYSTEM, ELECTRIC POWER TOOL, AND ELECTRONIC DEVICE EnviroMix, Inc. 2019-07-04 US disclosed
US-9353115-B2 Immune system modulators JANUS BIOTHERAPEUTICS, INC. (US) 2016-05-31 US disclosed
US-20130150642-A1 Preparation of an Olefin Oligomerization Catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-06-13 US disclosed
US-7732540-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20090018012-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130150642-A1 Preparation of an Olefin Oligomerization Catalyst PPOX, COASY, COG8 KDM4E 3686/4885HSD17B2 1856/4885ALDH1A1 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.