Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296397 | 0.79 | TDP1 (0.56) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2863159 | 0.79 | TDP1 (0.56) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15859 | 0.79 | TDP1 (0.75) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL26967080 | 0.76 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5129514 | 0.76 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5131831 | 0.76 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL7104676 | 0.76 | TDP1 (0.71) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4909852 | 0.76 | TDP1 (0.42) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10912951 | 0.74 | TDP1 (0.45) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28292955 | 0.74 | TDP1 (0.45) | TDP1PAOXCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656770-A2 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE-MEMBERED RING HETEROCYCLES | Syngenta Participations AG (CH) | 2020-05-27 | — | — | EP | disclosed |
| EP-3108955-B1 | SELF-WETTING POROUS MEMBRANES | PALL CORP (US) | 2017-12-06 | — | — | EP | disclosed |