Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511881 | 0.79 | TSHR (0.41) | TSHRALDH1A1 | |
| SCHEMBL6138137 | 0.76 | CA12 (0.38) | TDP1CYP2C9CYP2C19LMNAKDM4E | |
| SCHEMBL19677015 | 0.76 | TDP1 (0.52) | TDP1PAOXDPP7TERTCYP2C9 | |
| SCHEMBL15062382 | 0.74 | CA12 (0.41) | PAOXCYP2C9CYP2C19TSHRLMNA | |
| SCHEMBL7911598 | 0.72 | TDP1 (0.48) | TDP1PAOXDPP7TERTCYP2C9 | |
| SCHEMBL915610 | 0.71 | TDP1 (0.47) | TDP1PAOXDPP7TERTCYP2C9 | |
| SCHEMBL15859 | 0.70 | TDP1 (0.75) | TDP1PAOXDPP7TERTCYP2C9 | |
| SCHEMBL22323282 | 0.69 | TDP1 (0.50) | TDP1PAOXDPP7TERTCYP2C9 | |
| SCHEMBL27686958 | 0.69 | TP53 (0.33) | — | |
| SCHEMBL5131831 | 0.67 | TDP1 (0.71) | TDP1PAOXDPP7TERTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304023-B2 | coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free | WACKER CHEMIE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080107814-A1 | Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-05-08 | — | — | US | disclosed |