Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986291 | 0.78 | POLB (0.46) | MEN1ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL16153836 | 0.78 | POLB (0.46) | MEN1ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL10297510 | 0.75 | LMNA (0.40) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25122311 | 0.73 | CYP1A2 (0.44) | MEN1ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL8147035 | 0.73 | CA12 (0.38) | MEN1ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL14866257 | 0.73 | MAPT (0.48) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL470962 | 0.72 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL23050060 | 0.72 | LMNA (0.52) | ALDH1A1SMN1; SMN2ACHEGAA | |
| SCHEMBL14731548 | 0.72 | HTR2A (0.40) | MEN1KMT2ARAB9AACHEGAA | |
| SCHEMBL30663814 | 0.71 | TSHR (0.33) | MEN1ALDH1A1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251679-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT GLUCOSE TRANSPORTER | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-12-06 | — | — | EP | disclosed |