Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941588 | 0.84 | MEN1 (0.40) | CES2CES1AKT1MEN1KMT2A | |
| SCHEMBL13073861 | 0.82 | ALDH1A1 (0.42) | LMNAMAPTCYP3A4TDP1ESR1 | |
| SCHEMBL27414992 | 0.80 | AKT1 (0.41) | AKT1MEN1KMT2AATMLMNA | |
| SCHEMBL16900356 | 0.79 | F2 (0.38) | CES2CES1MEN1KMT2AATM | |
| SCHEMBL21697627 | 0.76 | CES2 (0.39) | CES2CES1AKT1MEN1KMT2A | |
| SCHEMBL18648715 | 0.73 | KMT2A (0.48) | CES2CES1AKT1MEN1KMT2A | |
| SCHEMBL6679191 | 0.72 | CES2 (0.46) | CES2CES1AKT1MEN1KMT2A | |
| SCHEMBL17030432 | 0.71 | ELANE (0.36) | CES2CES1AKT1MEN1KMT2A | |
| Propene SCHEMBL27837007 | 0.69 | AKT1 (0.44) | CES2CES1AKT1MEN1KMT2A | |
| SCHEMBL28208681 | 0.69 | CES2 (0.41) | CES2CES1AKT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251679-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT GLUCOSE TRANSPORTER | Mitsubishi Tanabe Pharma Corporation (JP) | 2017-12-06 | — | — | EP | disclosed |