Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190989 | 0.90 | HTT (0.66) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL27378768 | 0.86 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267326 | 0.85 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19677468 | 0.85 | HTT (0.59) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19001582 | 0.84 | AR (0.72) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL12267322 | 0.84 | AR (0.72) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL22043340 | 0.84 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL19193322 | 0.84 | HTT (0.58) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL22043203 | 0.83 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E | |
| SCHEMBL26461593 | 0.83 | HTT (0.57) | HTTHIF1AARKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252032-A1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2017-12-06 | — | — | EP | disclosed |