Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712511 | 0.84 | ALDH1A1 (0.44) | ALOX5BACE1CSNK2A1DPP4 | |
| SCHEMBL27570605 | 0.83 | DPP4 (0.52) | CNR1CNR2PSMB5ALOX5PDK2 | |
| SCHEMBL30012274 | 0.79 | ALDH1A1 (0.45) | CNR1CNR2PSMB5ALOX5PDK2 | |
| SCHEMBL4664590 | 0.79 | ALDH1A1 (0.41) | CSNK2A1DPP4TP53MMP2MMP3 | |
| SCHEMBL1967796 | 0.79 | FFAR1 (0.41) | ALOX5DPP4SIGMAR1 | |
| SCHEMBL28581448 | 0.77 | CNR1 (0.58) | CNR1CNR2PSMB5ALOX5PDK2 | |
| SCHEMBL29100401 | 0.77 | CNR1 (0.48) | CNR1CNR2PSMB5ALOX5PDK2 | |
| SCHEMBL10825675 | 0.76 | RARB (0.47) | CNR1CNR2PSMB5PDK2BACE1 | |
| SCHEMBL19567203 | 0.76 | CSNK2A1 (0.64) | CNR1CNR2PSMB5ALOX5PDK2 | |
| SCHEMBL27836086 | 0.75 | PSMB5 (0.52) | PSMB5GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334636-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010032147-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2010-03-25 | — | — | WO | disclosed |