Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15238788 | 0.87 | PPARA (0.50) | FFAR1FFAR4PPARALTB4R2PTGER1 | |
| SCHEMBL1309773 | 0.83 | ALDH1A1 (0.48) | FFAR1FFAR4LTB4R2PTGER1PTGER4 | |
| SCHEMBL8029291 | 0.82 | MAOB (0.47) | MAOBALOX5 | |
| SCHEMBL28961512 | 0.80 | DPP4 (0.48) | PTGER1PTGER4PTGER3PTGER2DPP4 | |
| SCHEMBL1967799 | 0.79 | CNR1 (0.41) | ALOX5DPP4SIGMAR1 | |
| SCHEMBL29993202 | 0.79 | HSD11B1 (0.47) | FFAR1MAOBPDE10ASIGMAR1 | |
| SCHEMBL8121859 | 0.79 | S1PR1 (0.42) | PPARADPP4 | |
| SCHEMBL712947 | 0.77 | HTR7 (0.44) | FFAR1FFAR4DPP4 | |
| SCHEMBL28195006 | 0.77 | FFAR1 (0.46) | FFAR1FFAR4PPARALTB4R2PTGER1 | |
| SCHEMBL13818518 | 0.76 | PPARA (0.51) | FFAR1FFAR4PPARALTB4R2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334636-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010032147-A2 | HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2010-03-25 | — | — | WO | disclosed |