Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.40 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967891 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EAKR1C3MAOBMEN1 | |
| SCHEMBL5489366 | 0.81 | CTBP2 (0.47) | ALDH1A1KDM4EAKR1C3MAOBKMT2A | |
| SCHEMBL5421666 | 0.81 | AKR1B1 (0.50) | ALDH1A1AKR1C3SLC22A12SLC2A9 | |
| SCHEMBL17595074 | 0.81 | AKR1B1 (0.50) | ALDH1A1AKR1C3SLC22A12SLC2A9 | |
| SCHEMBL11395760 | 0.81 | CTBP2 (0.47) | ALDH1A1KDM4EAKR1C3MAOBKMT2A | |
| SCHEMBL28250552 | 0.80 | AKR1C3 (0.44) | ALDH1A1KDM4EAKR1C3MAOBMEN1 | |
| SCHEMBL11393609 | 0.79 | AKR1C3 (0.43) | ALDH1A1KDM4EAKR1C3SLC22A12SLC2A9 | |
| SCHEMBL3628109 | 0.79 | CTBP2 (0.46) | ALDH1A1KDM4EAKR1C3MAOBMEN1 | |
| SCHEMBL6474057 | 0.79 | AKR1C3 (0.43) | AKR1C3SLC22A12SLC2A9APEX1 | |
| SCHEMBL6474065 | 0.79 | AKR1C3 (0.43) | AKR1C3SLC22A12SLC2A9APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172097-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing The Same | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| EP-2334650-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THEIR USE AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010031848-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THEIR USE AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172097-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing The Same | COX4I1, CYP2C19, CYP3A43 | ALDH1A1 249/4885KDM4E 2699/4885AKR1C3 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.