SCHEMBL5489366

SCHEMBL5489366

CC(=CCc1ccccc1C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.47
AKR1C3 P42330 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
HPGD P15428 2/20 0.44
ALDH1A1 P00352 2/20 0.44
SLC22A12 Q96S37 4/20 0.41
HTT P42858 1/20 0.41
MAOB P27338 1/20 0.41
PPARG P37231 1/20 0.40
SLC2A9 Q9NRM0 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP2C9 P11712 1/20 0.39
BACE1 P56817 1/20 0.39
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11395760 1.00 CTBP2 (0.47) CTBP2AKR1C3GAAKMT2AHPGD
SCHEMBL11399077 0.86 SLC22A12 (0.44) CTBP2AKR1C3GAAKMT2AALDH1A1
SCHEMBL11399081 0.86 SLC22A12 (0.44) CTBP2AKR1C3GAAKMT2AALDH1A1
SCHEMBL12003261 0.83 CTBP2 (0.45) CTBP2AKR1C3GAAKMT2AHPGD
SCHEMBL678767 0.83 CTBP2 (0.45) CTBP2AKR1C3GAAKMT2AHPGD
SCHEMBL5421666 0.82 AKR1B1 (0.50) AKR1C3HPGDALDH1A1SLC22A12HTT
SCHEMBL17595074 0.82 AKR1B1 (0.50) AKR1C3HPGDALDH1A1SLC22A12HTT
SCHEMBL6474057 0.81 AKR1C3 (0.43) AKR1C3SLC22A12PPARGSLC2A9CYP2C9
SCHEMBL6474065 0.81 AKR1C3 (0.43) AKR1C3SLC22A12PPARGSLC2A9CYP2C9
SCHEMBL1967891 0.81 ALDH1A1 (0.46) AKR1C3KMT2AALDH1A1SLC22A12MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US claimed
US-20070172772-A1 Microlens OMRON CORPORATION (JP) 2007-07-26 US disclosed
US-4284707-A Photocurable light-sensitive composition SOMAR MANUFACTURING CO., LTD. (JP) 1981-08-18 US disclosed