SCHEMBL19680120

SCHEMBL19680120

COC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)CC1OC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 5/20 0.48
▸ P2RY2 P41231 10/20 0.41
▸ P2RY4 P51582 5/20 0.41
▸ SLC28A1 O00337 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ SLC29A1 Q99808 1/20 0.41
▸ SLC28A3 Q9HAS3 1/20 0.41
▸ P2RY14 Q15391 1/20 0.40
▸ P2RY6 Q15077 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209782 1.00 DUT (0.48) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL19687652 1.00 DUT (0.48) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL19687651 1.00 DUT (0.48) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL13282414 1.00 DUT (0.48) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL12015134 0.89 DUT (0.47) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL26268704 0.89 DUT (0.47) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL12087561 0.89 DUT (0.47) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL22996114 0.89 DUT (0.46) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL18573361 0.89 DUT (0.46) DUTP2RY2P2RY4SLC28A1SLC28A2
SCHEMBL23343339 0.88 SLC28A1 (0.52) DUTP2RY2SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261284-A1 STABLE TARGET-EDITING GUIDE RNA TO WHICH CHEMICALLY MODIFIED NUCLEIC ACID IS INTRODUCED Fukuoka University (JP) 2023-10-18 — — EP disclosed
EP-3981436-A1 STABLE TARGET-EDITING GUIDE RNA HAVING CHEMICALLY MODIFIED NUCLEIC ACID INTRODUCED THEREINTO Fukuoka University (JP) 2022-04-13 — — EP disclosed
US-20210032282-A1 NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX AIST (JP) 2021-02-04 — — US disclosed
WO-2020246560-A1 STABLE TARGET-EDITING GUIDE RNA HAVING CHEMICALLY MODIFIED NUCLEIC ACID INTRODUCED THEREINTO 学校法人福岡大学 2020-12-10 — — WO disclosed
US-20170349623-A1 NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-12-07 — — US disclosed
US-20170349623-A1 NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349623-A1 NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX POLRMT, POLN, POLM DUT 163/4885P2RY2 3263/4885P2RY4 3843/4885
US-20210032282-A1 NUCLEIC ACID COMPLEX, METHOD FOR FORMING NUCLEIC ACID HYBRIDIZATION, PHARMACEUTICAL COMPOSITION, NUCLEIC ACID PROBE, AND COMPLEMENTARY-STRAND NUCLEIC ACID COMPLEX POLRMT, POLN, POLM DUT 163/4885P2RY2 3263/4885P2RY4 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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