Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840855 | 0.84 | KAT2B (0.45) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL1840270 | 0.83 | KAT2B (0.44) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL3317178 | 0.83 | KAT2B (0.44) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| SCHEMBL12659780 | 0.82 | EGFR (0.39) | CYP1A2CYP2D6DRD3HTR6JAK2 | |
| SCHEMBL12660152 | 0.81 | KAT2B (0.42) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| Hypochlorous Acid SCHEMBL3319939 | 0.81 | KAT2B (0.42) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| SCHEMBL19680480 | 0.81 | EGFR (0.38) | CYP1A2CYP2D6HRH3KDM4EGUCY1B2 | |
| SCHEMBL13016469 | 0.80 | ALDH1A1 (0.37) | CYP1A2CYP2D6KDM4EHTR1ADRD3 | |
| SCHEMBL1844055 | 0.80 | KAT2B (0.44) | KAT2BCYP1A2CYP2D6HRH3KDM4E | |
| SCHEMBL4411507 | 0.78 | HRH3 (0.49) | KAT2BCYP1A2CYP2D6HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | L'OREAL (FR) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349753-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING TWO PYRAZOLOPYRIDINE UNITS | KRT18, DSP, TMPO | KAT2B 1957/4885CYP1A2 1067/4885CYP2D6 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.