Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | HRH1 | P35367 | 4/20 | 0.69 |
| ▸ | DRD3 | P35462 | 4/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.69 |
| ▸ | HTR2A | P28223 | 3/20 | 0.69 |
| ▸ | HTR2B | P41595 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | FYN | P06241 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021980 | 0.93 | LMNA (0.62) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL12142463 | 0.91 | LMNA (0.59) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL8811661 | 0.90 | LMNA (0.59) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL6385060 | 0.90 | KCNH2 (0.70) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL10762463 | 0.90 | KCNH2 (0.70) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL1968825 | 0.90 | LMNA (0.58) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL1968701 | 0.87 | LMNA (0.57) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL11010415 | 0.87 | KCNH2 (0.58) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL1969921 | 0.86 | BCHE (0.61) | LMNAHRH1DRD3KCNH2HTR2A | |
| SCHEMBL10766174 | 0.86 | BCHE (0.62) | LMNAHRH1DRD3KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8022220-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-8022220-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| EP-1958935-B1 | Process for the production of terfenadine and carebastine derivatives with microorganisms | ALBANY MOLECULAR RES INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7691615-B2 | Process for the production of piperidine derivatives with microorganisms | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20020087003-A1 | Process for the production of piperidine derivatives with microorganisms | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2002-07-04 | — | — | US | disclosed |
| US-6201124-B1 | CONVERTING, WITH A PIPERIDINE COMPOUND, REGIOISOMERS UNDER NON-FRIEDEL-CRAFTS REACTION CONDITIONS | ALBANY MOLECULAR RESEARCH, INC. | 2001-03-13 | — | — | US | disclosed |
| US-6153754-A | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0868182-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0877733-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0877733-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0868182-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997023213-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
| WO-1997022344-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| WO-1997009983-A1 | PIPERIDINE DERIVATIVES AND PROCESSES FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | OR10J3, NR1H2, NR1H3 | LMNA 4284/4885HRH1 313/4885DRD3 448/4885 |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | HPD, PTMA, HAAO | LMNA 2264/4885HRH1 727/4885DRD3 687/4885 |
| US-20020087003-A1 | Process for the production of piperidine derivatives with microorganisms | CBR1, CBR3, DRD4 | LMNA 4093/4885HRH1 46/4885DRD3 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.