Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681580 | 0.94 | GPR84 (0.39) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL19681508 | 0.90 | GPR84 (0.36) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL19677888 | 0.83 | PLA2G1B (0.52) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL12515784 | 0.80 | GPR84 (0.46) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL12515911 | 0.80 | GPR84 (0.46) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL19681577 | 0.80 | GLS2 (0.38) | PLA2G1BPLA2G2ACACNA1FCHRM2ADRA2B | |
| SCHEMBL26039947 | 0.78 | GPR84 (0.47) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL17199810 | 0.78 | GPR84 (0.47) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL18789543 | 0.77 | GPR84 (0.43) | L3MBTL1PLA2G1BPLA2G2AGPR84FFAR4 | |
| SCHEMBL11504362 | 0.77 | FFAR1 (0.53) | PLA2G1BGPR84FFAR4FFAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | L3MBTL1 964/4885PLA2G1B 446/4885PLA2G2A 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.