Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402571 | 0.90 | CYP3A4 (0.53) | ACHE | |
| SCHEMBL16921118 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL25879431 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16921080 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16921138 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16921099 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16921154 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16921130 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL8533418 | 0.85 | ACHE (0.49) | ACHEEPHX1 | |
| SCHEMBL8757915 | 0.84 | ACHE (0.45) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202379-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2019-02-12 | — | — | US | disclosed |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ACHE 1599/4885EPHX1 1568/4885ZDHHC7 2164/4885 |
| US-10202379-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | PREP, UNG, DPP4 | ACHE 1599/4885EPHX1 1568/4885ZDHHC7 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.