Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921138 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL16921099 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL16921118 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL16921154 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL16921080 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL16921130 | 1.00 | ACHE (0.47) | ACHEEPHX1MMP9MMP8MMP14 | |
| SCHEMBL19681669 | 0.87 | ACHE (0.47) | ACHEEPHX1 | |
| SCHEMBL16475712 | 0.85 | ACHE (0.46) | ACHE | |
| SCHEMBL15149487 | 0.85 | PLA2G2A (0.46) | ACHE | |
| SCHEMBL19107903 | 0.84 | ACHE (0.68) | ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235358-A1 | HOST DEFENSE SUPPRESSING METHODS AND COMPOSITIONS FOR MODULATING A GENOME | FLAGSHIP PIONEERING INNOVATIONS VI, LLC | 2023-07-27 | — | — | US | disclosed |