Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682246 | 1.00 | AKT1 (0.32) | AKT1PLCG2PIK3R1AKT2PIK3CA | |
| SCHEMBL19682243 | 0.84 | CD209 (0.36) | — | |
| SCHEMBL19682267 | 0.81 | GJB2 (0.37) | — | |
| SCHEMBL19682251 | 0.81 | PTPN1 (0.35) | — | |
| SCHEMBL19682265 | 0.80 | GJB2 (0.35) | — | |
| SCHEMBL19682264 | 0.75 | SSTR1 (0.42) | — | |
| SCHEMBL19682305 | 0.73 | GJB2 (0.36) | — | |
| SCHEMBL19682240 | 0.72 | CD209 (0.48) | — | |
| SCHEMBL21258947 | 0.70 | PTPN1 (0.31) | — | |
| SCHEMBL19400293 | 0.69 | GJB2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348414-A1 | NOVEL SYNTHETIC ANTICANCER, ANTIFUNGAL, AND ANTIBACTERIAL VACCINES | WAYNE STATE UNIVERSITY (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348414-A1 | NOVEL SYNTHETIC ANTICANCER, ANTIFUNGAL, AND ANTIBACTERIAL VACCINES | ERG28, DDOST, STT3A | AKT1 827/4885PLCG2 492/4885PIK3R1 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.