SCHEMBL19682730

SCHEMBL19682730

CN1CCOc2c(S(=O)(=O)Cl)ccc(Cl)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.43
CHRM1 P11229 2/20 0.43
RRM1 P23921 2/20 0.43
RRM2B Q7LG56 2/20 0.43
L3MBTL1 Q9Y468 5/20 0.38
POLB P06746 2/20 0.38
HTR6 P50406 3/20 0.37
KMT2A Q03164 2/20 0.35
TP53 P04637 1/20 0.35
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
NOTUM Q6P988 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
FGB P02675 1/20 0.33
NPC1 O15118 1/20 0.33
PKM P14618 1/20 0.33
PKLR P30613 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19682914 0.82 CHRM2 (0.44) CHRM2CHRM1RRM1RRM2BL3MBTL1
SCHEMBL20872572 0.79 NOTUM (0.40) CHRM2CHRM1RRM1RRM2BHTR6
SCHEMBL19682783 0.76 CHRM2 (0.47) CHRM2CHRM1RRM1RRM2BHTR6
SCHEMBL29628597 0.76 NOTUM (0.38) CHRM2CHRM1RRM1RRM2BKMT2A
SCHEMBL19682726 0.76 NOTUM (0.38) CHRM2CHRM1RRM1RRM2BKMT2A
SCHEMBL19682920 0.75 CHRM2 (0.43) CHRM2CHRM1RRM1RRM2BL3MBTL1
SCHEMBL20872530 0.72 PKM (0.45) POLBKMT2AMEN1GAAPKM
SCHEMBL13184296 0.70 HTR2A (0.43) CHRM2CHRM1RRM1RRM2BL3MBTL1
SCHEMBL19682782 0.67 CHRM2 (0.45) CHRM2CHRM1RRM1RRM2BHTR6
SCHEMBL19682938 0.67 CHRM2 (0.40) CHRM2CHRM1RRM1RRM2BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017209155-A1 SULFONAMIDE COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2017-12-07 WO disclosed