Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | RRM1 | P23921 | 5/20 | 0.45 |
| ▸ | RRM2B | Q7LG56 | 5/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682783 | 0.86 | CHRM2 (0.47) | CHRM2CHRM1RRM1RRM2BHTR6 | |
| SCHEMBL20889321 | 0.76 | CHRM2 (0.46) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL19682914 | 0.72 | CHRM2 (0.44) | CHRM2CHRM1RRM1RRM2BHTR6 | |
| SCHEMBL19682730 | 0.67 | CHRM2 (0.43) | CHRM2CHRM1RRM1RRM2BHTR6 | |
| SCHEMBL19682915 | 0.66 | CHRM2 (0.49) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL20872572 | 0.62 | NOTUM (0.40) | CHRM2CHRM1RRM1RRM2BHTR6 | |
| SCHEMBL20872530 | 0.61 | PKM (0.45) | SMN1; SMN2LMNA | |
| SCHEMBL2037190 | 0.61 | PIK3CD (0.52) | — | |
| SCHEMBL19682726 | 0.59 | NOTUM (0.38) | CHRM2CHRM1RRM1RRM2BSMN1; SMN2 | |
| SCHEMBL29628597 | 0.59 | NOTUM (0.38) | CHRM2CHRM1RRM1RRM2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017209155-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-12-07 | — | — | WO | disclosed |