SCHEMBL19683022

SCHEMBL19683022

CN(Cc1ccc(/C=C/C(=O)Nc2ccccc2N)cc1)CC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 14/20 0.71
▸ HDAC6 Q9UBN7 4/20 0.71
▸ HDAC2 Q92769 3/20 0.71
▸ HDAC3 O15379 3/20 0.71
▸ HDAC5 Q9UQL6 3/20 0.71
▸ HDAC4 P56524 2/20 0.71
▸ HDAC10 Q969S8 2/20 0.71
▸ HDAC8 Q9BY41 1/20 0.71
▸ RARB P10826 1/20 0.54
▸ KDM1A O60341 2/20 0.52
▸ MAOA P21397 2/20 0.52
▸ MAOB P27338 1/20 0.47
▸ P2RX7 Q99572 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17478531 1.00 HDAC1 (0.71) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17478501 1.00 HDAC1 (0.71) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL19666050 1.00 HDAC1 (0.71) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL19682890 0.90 HDAC1 (0.57) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17478445 0.90 HDAC6 (0.73) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17478446 0.90 HDAC6 (0.73) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL18088443 0.89 HDAC1 (0.64) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17483933 0.89 HDAC1 (0.64) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17483902 0.87 HDAC1 (0.67) HDAC1HDAC6HDAC2HDAC3HDAC5
SCHEMBL17483897 0.87 HDAC3 (0.67) HDAC1HDAC6HDAC2HDAC3HDAC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574593-A Primer coating ink for metal surface and preparation method and application thereof 中钞油墨有限公司 2026-02-27 — — CN claimed
CN-122037657-A Ink composition and application thereof 昆山百柔新材料技术有限公司 2026-05-15 — — CN disclosed
EP-4720766-A1 NARROW FIELD OF VIEW ANGULAR LIGHT CONTROL FILM 3M Innovative Properties Company (US) 2026-04-08 — — EP disclosed
CN-121574593-A Primer coating ink for metal surface and preparation method and application thereof 中钞油墨有限公司 2026-02-27 — — CN disclosed
US-20260022277-A1 CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2026-01-22 — — US disclosed
US-12491270-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography THE GENERAL HOSPITAL CORPORATION (US) 2025-12-09 — — US disclosed
WO-2025215194-A1 ENHANCED REMOVABILITY OF NAIL COATINGS USING ACIDIC COPOLYMERS FOR TRIGGERED REMOVAL WITH AQUEOUS BASED REMOVER ARKEMA FRANCE (FR) 2025-10-16 — — WO disclosed
US-12418013-B2 Method of solvent-free manufacturing of composite electrodes incorporating radiation curable binders UT-BATTELLE, LLC (US) 2025-09-16 — — US disclosed
EP-3955900-B1 POLYMERIC CAPSULES PROCTER & GAMBLE (US) 2025-07-23 — — EP disclosed
EP-3701299-B1 METHOD OF MAKING A RETROREFLECTIVE ARTICLE COMPRISING LOCALLY-LAMINATED REFLECTIVE LAYERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-05-28 — — EP disclosed
US-11289689-B2 Method of solvent-free manufacturing of composite electrodes incorporating radiation curable binders UTBATTELE, LLC (US) 2022-03-29 — — US disclosed
US-11278857-B2 Polymeric capsules THE PROCTER & GAMBLE COMPANY (US) 2022-03-22 — — US disclosed
CN-110475827-B Radiation curable ink compositions, printed articles, and methods of using the same 花王株式会社 2022-02-15 — — CN disclosed
CN-114040773-A Lysin and derivatives thereof having bactericidal activity against pseudomonas aeruginosa in the presence of human serum 康特拉费克特公司 2022-02-11 — — CN disclosed
US-20210030899-A1 IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY THE GENERAL HOSPITAL CORPORATION 2021-02-04 — — US disclosed
US-10842891-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography THE GENERAL HOSPITAL CORPORATION (US) 2020-11-24 — — US disclosed
US-20190240357-A1 IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY THE GENERAL HOSPITAL CORPORATION 2019-08-08 — — US disclosed
US-10188756-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography THE GENERAL HOSPITAL CORPORATION (US) 2019-01-29 — — US disclosed
US-20170349540-A1 HISTONE DEACETYLASE INHIBITORS THE GENERAL HOSPITAL CORPORATION 2017-12-07 — — US disclosed
US-20170349540-A1 HISTONE DEACETYLASE INHIBITORS THE GENERAL HOSPITAL CORPORATION 2017-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240357-A1 IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY HDAC1, HDAC11, HDAC3 HDAC1 1/4885HDAC6 13/4885HDAC2 4/4885
US-10188756-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography HDAC1, HDAC11, HDAC3 HDAC1 1/4885HDAC6 13/4885HDAC2 4/4885
US-20210030899-A1 IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY HDAC1, HDAC11, HDAC3 HDAC1 1/4885HDAC6 13/4885HDAC2 4/4885
US-12491270-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography HDAC1, HDAC11, HDAC3 HDAC1 1/4885HDAC6 13/4885HDAC2 4/4885
US-20170349540-A1 HISTONE DEACETYLASE INHIBITORS HDAC1, HDAC11, HDAC5 HDAC1 1/4885HDAC6 10/4885HDAC2 4/4885
US-20260022277-A1 CURABLE COMPOSITIONS MTDH, MYO1G, TPM3 HDAC1 3039/4885HDAC6 1374/4885HDAC2 4078/4885
US-10842891-B2 Imaging histone deacetylases with a radiotracer using positron emission tomography HDAC1, HDAC11, HDAC3 HDAC1 1/4885HDAC6 13/4885HDAC2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback