Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527241 | 0.88 | CYP19A1 (0.61) | CYP19A1BRS3NOTUMFAAHMGLL | |
| SCHEMBL14567879 | 0.87 | CYP19A1 (0.63) | CYP19A1BRS3NOTUMFAAHMGLL | |
| SCHEMBL19683363 | 0.86 | CYP19A1 (0.53) | CYP19A1BRS3NOTUMFAAHMGLL | |
| SCHEMBL9969482 | 0.83 | NOTUM (0.50) | CYP19A1BRS3NOTUMBCHE | |
| SCHEMBL12844428 | 0.77 | CYP19A1 (0.59) | CYP19A1BRS3NOTUMMGLL | |
| SCHEMBL9969400 | 0.76 | NOTUM (0.54) | CYP19A1BRS3NOTUM | |
| SCHEMBL4966052 | 0.73 | NOTUM (0.50) | CYP19A1BRS3NOTUMHTR2A | |
| SCHEMBL21156935 | 0.72 | NOTUM (0.54) | CYP19A1BRS3NOTUM | |
| SCHEMBL6853891 | 0.71 | NOTUM (0.51) | CYP19A1BRS3NOTUMCA2TBXAS1 | |
| SCHEMBL12411773 | 0.70 | NOTUM (0.63) | CYP19A1BRS3NOTUMMGLLADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | CYP19A1 709/4885BRS3 794/4885NOTUM 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.