Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 6/20 | 0.43 |
| ▸ | GABRD | O14764 | 6/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.43 |
| ▸ | GABRE | P78334 | 6/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683305 | 0.79 | PAX8 (0.41) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL19683576 | 0.79 | MAOB (0.60) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL19683569 | 0.78 | GABRP (0.55) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL11643881 | 0.75 | MAOB (0.63) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL10173044 | 0.73 | MAOB (0.74) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL11643021 | 0.73 | MAOB (0.62) | MAOBMAOATNKSCYP3A4 | |
| SCHEMBL19683308 | 0.72 | CYP1A1 (0.36) | MAOBMAOATNKSAPP | |
| SCHEMBL19683462 | 0.71 | MAOB (0.47) | MAOBMAOATNKSGABRPGABRD | |
| SCHEMBL19683385 | 0.70 | PIM1 (0.40) | — | |
| SCHEMBL30176891 | 0.69 | MAOB (0.59) | MAOBMAOATNKSESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |