Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 6/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.31 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683621 | 0.91 | PRMT1 (0.44) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL20878954 | 0.86 | PRMT1 (0.38) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL23047341 | 0.85 | PRMT1 (0.42) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL23047328 | 0.82 | EGFR (0.44) | PRMT1CARM1EGFRTTBK1TTBK2 | |
| SCHEMBL20878857 | 0.82 | PRMT1 (0.41) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL23047342 | 0.82 | PRMT1 (0.41) | PRMT1CARM1EGFRERBB2TTBK1 | |
| SCHEMBL23047326 | 0.79 | PRMT1 (0.39) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL20878934 | 0.77 | PRMT1 (0.37) | PRMT1CARM1LIMK1EGFRERBB2 | |
| SCHEMBL20878945 | 0.77 | EIF2AK2 (0.42) | LIMK1ERBB2 | |
| SCHEMBL19683752 | 0.77 | PLK4 (0.38) | PRMT1TTBK1TTBK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |