Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683694 | 0.82 | JAK2 (0.46) | JAK2SYKERBB2 | |
| SCHEMBL23047326 | 0.81 | PRMT1 (0.39) | PRMT1EGFRERBB2CARM1TTBK1 | |
| SCHEMBL19683782 | 0.81 | EGFR (0.45) | ALDH1A1JAK2SYKEGFRERBB2 | |
| SCHEMBL20878954 | 0.81 | PRMT1 (0.38) | PRMT1EGFRERBB2CARM1TTBK1 | |
| SCHEMBL20878968 | 0.80 | SRC (0.44) | EPHX2BTKEGFRERBB2 | |
| SCHEMBL23047341 | 0.80 | PRMT1 (0.42) | PRMT1ALDH1A1BTKEGFRERBB2 | |
| SCHEMBL23047342 | 0.79 | PRMT1 (0.41) | PRMT1MEN1KMT2AJAK2SYK | |
| SCHEMBL20878857 | 0.79 | PRMT1 (0.41) | PRMT1EGFRERBB2CARM1TTBK1 | |
| SCHEMBL23047328 | 0.79 | EGFR (0.44) | TDP1MAPK1PRMT1ALDH1A1TSHR | |
| SCHEMBL24671954 | 0.79 | SRC (0.40) | PRMT1BTKCARM1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |