SCHEMBL24671954

SCHEMBL24671954

CC(C)Nc1ncnc(N)c1C(=N)c1ccc(NC=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.40
PRMT1 Q99873 4/20 0.37
LIMK1 P53667 3/20 0.36
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
PIK3CD O00329 4/20 0.31
PIK3R1 P27986 1/20 0.31
BTK Q06187 1/20 0.31
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MAP4K4 O95819 1/20 0.30
CARM1 Q86X55 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13430257 0.81 SRC (0.54) SRCLIMK1HTTSMN1; SMN2MAP4K4
SCHEMBL23047328 0.80 EGFR (0.44) PRMT1SMN1; SMN2CARM1
SCHEMBL20878857 0.80 PRMT1 (0.41) PRMT1LIMK1CARM1
SCHEMBL23047342 0.80 PRMT1 (0.41) PRMT1CARM1
SCHEMBL23047341 0.80 PRMT1 (0.42) PRMT1LIMK1BTKMAP4K4CARM1
SCHEMBL24671042 0.80 CYP2C19 (0.36) SRCPRMT1PIK3CDBTKLMNA
SCHEMBL19683791 0.79 EPHX2 (0.40) PRMT1BTKHTTCARM1
SCHEMBL21082764 0.79 DYRK1A (0.37) SRCMAPK14LMNAHTTSMN1; SMN2
SCHEMBL23047326 0.79 PRMT1 (0.39) PRMT1LIMK1LMNACARM1
SCHEMBL19683621 0.78 PRMT1 (0.44) PRMT1LIMK1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4043465-A1 SUBSTITUTED AROMATIC FUSED RING DERIVATIVE AND COMPOSITION COMPRISING SAME, AND USE THEREOF Shenzhen TargetRx, Inc. (CN) 2022-08-17 EP disclosed