Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.64 |
| ▸ | FLT3 | P36888 | 4/20 | 0.64 |
| ▸ | BTK | Q06187 | 3/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | RET | P07949 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.64 |
| ▸ | CDK11B | P21127 | 1/20 | 0.64 |
| ▸ | CCNC | P24863 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 1/20 | 0.64 |
| ▸ | CDK8 | P49336 | 1/20 | 0.64 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.64 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.64 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683819 | 0.82 | FLT3 (0.81) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL23047323 | 0.81 | BTK (0.65) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683613 | 0.81 | BTK (0.63) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL23047312 | 0.79 | ATR (0.45) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683590 | 0.79 | FLT3 (0.72) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683612 | 0.78 | RET (1.00) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683779 | 0.78 | FLT3 (0.77) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683689 | 0.78 | FLT3 (0.74) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL20873189 | 0.78 | FLT3 (0.70) | LCKFLT3BTKCSF1RRET | |
| SCHEMBL19683609 | 0.78 | LCK (0.60) | LCKFLT3BTKCSF1RRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |