Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | AHSA1 | O95433 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640095 | 0.87 | ELANE (0.49) | AHSA1IKBKBKMT2AMAPTMEN1 | |
| SCHEMBL3241127 | 0.70 | PLA2G10 (0.54) | PTGS1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL2857377 | 0.70 | CCR1 (0.64) | GAAKMT2AMEN1 | |
| SCHEMBL19639775 | 0.69 | RXFP1 (0.47) | MAPTKDRRXFP1 | |
| SCHEMBL11798167 | 0.69 | KIF11 (0.61) | PTGS1GAAKMT2AMAPTMEN1 | |
| SCHEMBL10467154 | 0.69 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL20984529 | 0.69 | MAPT (0.58) | GAAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL28871752 | 0.69 | TLR7 (0.70) | PTGS1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL28020270 | 0.69 | KCNK3 (0.65) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL19640079 | 0.68 | ELANE (0.47) | GAAMAPTLMNANPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207432-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |