Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25781653 | 0.91 | CCR1 (0.53) | CCR1MLYCD | |
| SCHEMBL25781908 | 0.81 | CCR1 (0.66) | CCR1MAPK14MLYCDMEN1PLA2G1B | |
| SCHEMBL2859642 | 0.81 | CCR1 (0.73) | CCR1MAPK14 | |
| SCHEMBL2850143 | 0.80 | CCR1 (0.85) | CCR1MAPK14 | |
| SCHEMBL25078338 | 0.78 | CCR1 (0.59) | CCR1MAPK14MLYCDMEN1PLA2G1B | |
| SCHEMBL1256358 | 0.78 | CCR1 (1.00) | CCR1 | |
| SCHEMBL25781577 | 0.77 | TACR1 (0.48) | MLYCDMEN1KMT2A | |
| SCHEMBL5261051 | 0.77 | MLYCD (0.80) | MAPK14MLYCDMEN1PLA2G1BCYP1A2 | |
| SCHEMBL2858213 | 0.77 | CCR1 (0.69) | CCR1MAPK14GAA | |
| SCHEMBL10467154 | 0.76 | KMT2A (0.53) | MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |