⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684546 | 0.81 | DYRK1A (0.41) | — | |
| SCHEMBL13134043 | 0.80 | FPR3 (0.31) | — | |
| SCHEMBL20911119 | 0.77 | DYRK1A (0.31) | — | |
| SCHEMBL19684528 | 0.73 | EIF2AK3 (0.34) | — | |
| SCHEMBL19684547 | 0.68 | LRRK2 (0.33) | — | |
| SCHEMBL31514706 | 0.68 | CDK1 (0.35) | — | |
| SCHEMBL20351604 | 0.65 | PDK2 (0.30) | — | |
| SCHEMBL18520802 | 0.63 | TYMS (0.44) | — | |
| SCHEMBL20351602 | 0.63 | ADK (0.31) | — | |
| SCHEMBL15872011 | 0.61 | KDM5B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10709709-B2 | Substituted carbonucleoside derivatives useful as anticancer agents | PFIZER INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190111060-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2019-04-18 | — | — | US | disclosed |
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2017-12-07 | — | — | US | disclosed |