Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 9/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17222600 | 0.78 | S1PR3 (0.55) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL30154451 | 0.77 | S1PR3 (0.44) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL23832231 | 0.77 | S1PR3 (0.44) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL19862704 | 0.77 | ESR1 (0.49) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL5365140 | 0.77 | S1PR3 (0.46) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL5388435 | 0.73 | SMN1; SMN2 (0.49) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL5388430 | 0.73 | SMN1; SMN2 (0.49) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL5390593 | 0.73 | SMN1; SMN2 (0.49) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL5317090 | 0.71 | AKR1C3 (0.54) | CYP2C19NPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL27086889 | 0.71 | S1PR3 (0.46) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023543-B2 | Inhibitors of lysine specific demethylase-1 | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170349556-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | QUANTIEL PHARMACEUTICALS, INC. | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349556-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | KDM1B, KDM1A, KDM3A | S1PR3 2173/4885S1PR1 1506/4885CYP11B1 2717/4885 |
| US-10023543-B2 | Inhibitors of lysine specific demethylase-1 | KDM1B, KDM1A, KDM3A | S1PR3 2173/4885S1PR1 1506/4885CYP11B1 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.