Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211567 | 0.80 | CACNA1H (0.43) | S1PR3ACACBCACNA1HCTSD | |
| SCHEMBL19685162 | 0.77 | S1PR3 (0.48) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL7743300 | 0.76 | CPB2 (0.48) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL17222600 | 0.76 | S1PR3 (0.55) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A | |
| SCHEMBL2403690 | 0.74 | ESR1 (0.60) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23494950 | 0.73 | ESR1 (0.63) | ESR1ESR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5365140 | 0.72 | S1PR3 (0.46) | S1PR3S1PR1CYP11B1CYP11B2MAOB | |
| SCHEMBL9278424 | 0.72 | ESR1 (0.54) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL9896903 | 0.72 | ESR1 (0.73) | ESR1ESR2MEN1KMT2ALDHA | |
| SCHEMBL5388435 | 0.71 | SMN1; SMN2 (0.49) | S1PR3S1PR1CYP11B1CYP11B2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031658-A1 | TREATMENT OF RELAPSED AND/OR REFRACTORY SOLID TUMORS AND NON-HODGKIN'S LYMPHOMAS | CELGENE CORPORATION (US) | 2018-02-15 | — | — | WO | disclosed |