Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 14/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832231 | 1.00 | S1PR3 (0.44) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL30154432 | 0.84 | S1PR3 (0.45) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL23832197 | 0.84 | S1PR3 (0.45) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL5365140 | 0.83 | S1PR3 (0.46) | S1PR3S1PR1CYP11B1CYP11B2TRPA1 | |
| SCHEMBL23832221 | 0.81 | ACACB (0.41) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL30154447 | 0.81 | ACACB (0.41) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL23832213 | 0.78 | SLC6A3 (0.42) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL19926033 | 0.78 | LMNA (0.47) | ALDH1A1 | |
| SCHEMBL30154435 | 0.78 | SLC6A3 (0.42) | S1PR3S1PR1ALDH1A1 | |
| SCHEMBL29875423 | 0.78 | LMNA (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823097-A | PHD inhibitor compounds, compositions and uses | 阿克比治疗有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-115551845-B | PHD inhibitor compounds, compositions and uses | 阿克比治疗有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115551845-A | PHD inhibitor compounds, compositions and uses | 阿克比治疗有限公司 | 2022-12-30 | — | — | CN | disclosed |