Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19685663 | 1.00 | CASP1 (0.45) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL18067131 | 0.89 | ALDH1A1 (0.43) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL18067130 | 0.89 | ALDH1A1 (0.43) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL1743237 | 0.88 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL1744521 | 0.88 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL29708059 | 0.88 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL19827999 | 0.88 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL15726979 | 0.88 | ALDH1A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL22065039 | 0.87 | BTN3A1 (0.51) | CASP1MAPTALDH1A1GAAMRGPRX4 | |
| SCHEMBL15203143 | 0.87 | BTN3A1 (0.42) | CASP1MAPTALDH1A1GAAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207993-A1 | CANCER TREATMENTS | NUCANA BIOMED LIMITED (GB) | 2017-12-07 | — | — | WO | disclosed |