SCHEMBL19685733

SCHEMBL19685733

Cc1cn(C)c2cc(N3c4ccccc4[Si]4(c5ccccc5-c5ccccc54)c4ccccc43)ccc2c1=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 1/20 0.32
TP53 P04637 1/20 0.32
MAOB P27338 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NTRK1 P04629 1/20 0.30
POLB P06746 1/20 0.30
BRD1 O95696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685816 0.92 KMT2A (0.35) MEN1KMT2AALDH1A1KDM4EBRD4
SCHEMBL19685735 0.90 MAOB (0.33) ALDH1A1TP53MAOBPOLB
SCHEMBL19686036 0.88 MEN1 (0.33) MEN1KMT2A
SCHEMBL19685859 0.84 BRD4 (0.43) MEN1KMT2ABRD4L3MBTL1
SCHEMBL19686021 0.84 BRD4 (0.40) MEN1KMT2ABRD4
SCHEMBL19685815 0.83 ALDH1A1 (0.38) MEN1KMT2AALDH1A1BRD4TP53
SCHEMBL19686170 0.81 SCN2B (0.36) MEN1KMT2A
SCHEMBL19685867 0.81 MEN1 (0.35) MEN1KMT2AALDH1A1KDM4EBRD4
SCHEMBL19685814 0.81 KMT2A (0.33) MEN1KMT2AALDH1A1KDM4ETP53
SCHEMBL19685863 0.81 MEN1 (0.35) MEN1KMT2AALDH1A1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885ALDH1A1 572/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885ALDH1A1 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.