SCHEMBL19685919

SCHEMBL19685919

Cc1ccc2c(c1)C1(c3ccccc3Oc3ccccc31)c1cc(C)ccc1N2c1ccc2c(=O)c(C)cn(-c3ccccc3)c2c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CD74 P04233 1/20 0.32
MIF P14174 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
HPGD P15428 1/20 0.30
BLM P54132 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685976 0.93 SCN2B (0.32) KDM4EALDH1A1CYP1A2HPGDBLM
SCHEMBL19685922 0.92 MAPK8 (0.32)
SCHEMBL19685870 0.91 MAPK8 (0.36) CD74MIF
SCHEMBL19686033 0.89 PGR (0.32) KDM4EALDH1A1CYP1A2HPGDBLM
SCHEMBL19685865 0.89 TP53 (0.34)
SCHEMBL19685990 0.86 KDM4E (0.31) KDM4EALDH1A1CYP1A2HPGDBLM
SCHEMBL19685933 0.86 ESR1 (0.32) KDM4EALDH1A1CYP1A2HPGDBLM
SCHEMBL19686172 0.84 SCN2B (0.34)
SCHEMBL19686363 0.83 MIF (0.33) CD74MIFKDM4EALDH1A1CYP1A2
SCHEMBL19685875 0.83 SCN2B (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS CD74 4814/4885MIF 2886/4885KDM4E 1138/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS CD74 4814/4885MIF 2886/4885KDM4E 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.