Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19685948 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL19685683 | 0.90 | KDM4E (0.38) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL17850996 | 0.84 | PTGER4 (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL19685676 | 0.82 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL19685861 | 0.80 | TP53 (0.35) | ALDH1A1MAPTAGTR1MAOBRAB9A | |
| SCHEMBL19685947 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL19686086 | 0.79 | BRD4 (0.40) | MAPTAGTR1MEN1KMT2A | |
| SCHEMBL19686363 | 0.78 | MIF (0.33) | ALDH1A1KDM4EHPGDHSD17B10AGTR1 | |
| SCHEMBL19685674 | 0.77 | KDM4E (0.36) | ALDH1A1KDM4EHPGDUSP2HSD17B10 | |
| SCHEMBL19685946 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | CYC1, CCNA1, CYCS | ALDH1A1 572/4885KDM4E 1138/4885HPGD 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.