Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886158 | 0.83 | CYP4F2 (0.42) | ALDH1A1MAPTTSHRCYP4F2CYP4A11 | |
| SCHEMBL19686005 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTTSHRCYP4F2CYP4A11 | |
| SCHEMBL16125671 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTTSHRCYP4F2CYP4A11 | |
| SCHEMBL19682908 | 0.79 | CYP4F2 (0.36) | ALDH1A1MAPTTSHRCYP4F2CYP4A11 | |
| SCHEMBL79588 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL28293945 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL13269637 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRNPSR1GLO1 | |
| SCHEMBL25905083 | 0.77 | THRB (0.36) | ALDH1A1TSHRCYP4F2CYP4A11LMNA | |
| SCHEMBL22758423 | 0.76 | CYP4F2 (0.43) | ALDH1A1MAPTTSHRCYP4F2CYP4A11 | |
| SCHEMBL28099320 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTTSHRNPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196481-B2 | Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof | SIRRUS, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170349700-A1 | POLYMER AND OTHER COMPOUNDS FUNCTIONALIZED WITH TERMINAL 1,1-DISUBSTITUTED ALKENE MONOMER(S) AND METHODS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |