SCHEMBL19686156

SCHEMBL19686156

Cc1cn(-c2ccccc2)c2cc(N3c4ccccc4-c4ccccc4Sc4ccccc4-c4ccccc43)ccc2c1=O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 3/20 0.32
CES2 O00748 1/20 0.32
BCHE P06276 1/20 0.32
GAA P10253 1/20 0.32
CES1 P23141 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SCN2B O60939 1/20 0.32
SCN1A P35498 1/20 0.32
SCN1B Q07699 1/20 0.32
SCN5A Q14524 1/20 0.32
SCN9A Q15858 1/20 0.32
MAPK8 P45983 11/20 0.32
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685867 0.87 MEN1 (0.35) MEN1KMT2ALMNAALDH1A1HDAC6
SCHEMBL19685878 0.85 SCN2B (0.37) MEN1KMT2AALDH1A1SCN2BSCN1A
SCHEMBL19686362 0.85 MEN1 (0.33) MEN1KMT2AALDH1A1CES2BCHE
SCHEMBL19685925 0.84 MAPK8 (0.32) SCN2BSCN1ASCN1BSCN5ASCN9A
SCHEMBL19686146 0.83 ESR1 (0.38) MEN1KMT2ALMNAALDH1A1CES2
SCHEMBL19686035 0.80 MEN1 (0.33) MEN1KMT2AALDH1A1SCN2BSCN1A
SCHEMBL19686036 0.80 MEN1 (0.33) MEN1KMT2ASCN2BSCN1ASCN1B
SCHEMBL19686363 0.77 MIF (0.33) MEN1KMT2AALDH1A1GAANPSR1
SCHEMBL19686033 0.77 PGR (0.32) MEN1KMT2AALDH1A1NPSR1SCN2B
SCHEMBL19686346 0.77 MAPK8 (0.33) ALDH1A1SCN2BSCN1ASCN1BSCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885LMNA 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.