⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249982 | 0.75 | NPC1 (0.30) | — | |
| SCHEMBL19605727 | 0.70 | NPC1 (0.30) | — | |
| SCHEMBL7199377 | 0.67 | LMNA (0.37) | — | |
| SCHEMBL20118243 | 0.66 | NPC1 (0.30) | — | |
| SCHEMBL12471588 | 0.66 | RAB9A (0.36) | — | |
| SCHEMBL497104 | 0.65 | — | — | |
| SCHEMBL2066981 | 0.63 | — | — | |
| SCHEMBL28675081 | 0.62 | — | — | |
| SCHEMBL18691332 | 0.61 | — | — | |
| SCHEMBL12333661 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210395-A1 | USE OF EZH2 INHIBITORS FOR TREATING CANCER | Epizyme, Inc. (US) | 2017-12-07 | — | — | WO | disclosed |